| Walt Disney Co. | Walt Disney | state | 2021 | $570,000,000 | | MEGADEAL  |
| Scripps Research Institute | Scripps Research Institute | multiple | 2003 | $545,000,000 | | MEGADEAL |
| Northrop Grumman | Northrop Grumman | multiple | 2014 | $471,005,000 | | MEGADEAL |
| Burnham Institute for Medical Research | Sanford-Burnham Medical Research Institute | multiple | 2006 | $233,600,000 | | MEGADEAL |
| Max Planck Florida Corporation | Max Planck Florida Institute | multiple | 2008 | $193,000,000 | | MEGADEAL |
| Burnham Institute for Medical Research | Sanford-Burnham Medical Research Institute | state | 2006 | $155,272,000 | | grant |
| Digital Domain Media Group | Searchlight Capital | multiple | 2009 | $135,000,000 | | MEGADEAL |
| Vaccine & Gene Therapy Institute | Vaccine & Gene Therapy Institute | multiple | 2008 | $117,800,000 | | MEGADEAL |
| Max Planck Florida Corporation | Max Planck Florida Institute | state | 2007 | $94,090,000 | | grant |
| Hertz | Hertz | multiple | 2013 | $84,800,000 | | MEGADEAL |
| Torrey Pines Institute for Molecular Studies | Torrey Pines Institute For Molecular Studies | multiple | 2006 | $81,900,000 | | MEGADEAL |
| Hussman Institute- University of Miami - Leonard M. Miller School of Medicine | Hussman Institute for Human Genomics | state | 2007 | $80,000,000 | | grant |
| Hussman Institute for Human Genomics (University of Miami Miller School of Medicine) | Hussman Institute for Human Genomics | state | 2008 | $80,000,000 | | MEGADEAL |
| Blue Origin | Blue Origin LLC | multiple | 2015 | $65,550,000 | | megadeal |
| The Vaccine and Gene Therapy Institute of Florida (VGTI Florida) | Vaccine & Gene Therapy Institute | state | 2007 | $60,000,000 | | grant |
| Aldi, Inc. C/O (Florida South Division LLC) | Aldi | local | 2015 | $37,343,414 | | tax credit/rebate |
| Aldi, Inc. C/O (Florida South Division LLC) | Aldi | local | 2016 | $37,343,414 | | tax credit/rebate |
| Fis (Project Sharp) | | local | 2019 | $27,500,000 | | multiple |
| Torrey Pines Institute for Molecular Studies, Inc. | Torrey Pines Institute For Molecular Studies | state | 2006 | $24,728,000 | | grant |
| BDB Miami, LLC | | local | 2009 | $24,000,000 | | tax increment financing |
| Eagle Lng Partners | | local | 2019 | $23,000,000 | | grant |
| Dun And Bradstreet Corporation | Dun & Bradstreet | local | 2021 | $21,000,000 | | multiple |
| Wyndcrest DD Florida, Inc. | | state | 2009 | $20,000,000 | | grant |
| SRI International | | state | 2006 | $20,000,000 | | grant |
| Flagler Interchange | | local | 1999 | $17,600,000 | | grant |
| River City Marketpl. | | local | 2004 | $16,000,000 | | grant |
| Southeast Toyota | | local | 1999 | $15,137,500 | | grant |
| Charles Stark Draper Laboratory, Inc. | | state | 2008 | $15,000,000 | | grant |
| H. Lee Moffitt Cancer Center & Research Institute, Inc. | | state | 2007 | $15,000,000 | | grant |
| T. Rowe Price Associates, Inc. | T. Rowe Price | state | 2009 | $12,000,000 | | grant |
| Metal Container Corporation | Anheuser-Busch InBev | local | 2016 | $12,000,000 | | grant |
| Spirit Aerosystems, Inc. | Spirit AeroSystems | state | 2007 | $11,585,800 | | grant |
| Universal Studios Escape | Comcast | state | 1998 | $10,000,000 | | grant |
| Amazon | Amazon.com | local | 2016 | $10,000,000 | | grant |
| Pratt & Whitney - Liquid Space Propulsion | RTX Corporation | state | 2000 | $8,750,000 | | grant |
| Northrop Grumman Systems Corporation | Northrop Grumman | state | 2014 | $8,700,000 | | grant |
| Agere Systems | | state | 1998 | $8,500,000 | | grant |
| Magic Leap, Inc. | | state | 2017 | $8,075,000 | | tax credit/rebate |
| STARZ MIAMI PRODUCTIONS, LLC | | state | 2014 | $8,000,000 | | tax credit/rebate |
| Fidelity National Financial, Inc. & Subsidiaries | Fidelity National Financial | state | 2003 | $7,875,000 | | tax credit/rebate |
| MESQUITE PRODUCTIONS, INC. | | state | 2016 | $7,804,019 | | tax credit/rebate |
| Royal Concrete Concepts, Inc | | state | 2005 | $7,500,000 | | tax credit/rebate |
| Peninsula at St. Johns Center Phase II | | local | 1999 | $7,500,000 | | grant |
| The Strand at St. Johns Center Phase I | | local | 2001 | $7,500,000 | | grant |
| Buckeye Technologies, Inc. | | state | 2009 | $7,381,000 | | grant |
| Torrey Pines Institute for Molecular Studies, Inc. | Torrey Pines Institute For Molecular Studies | state | 2006 | $7,272,000 | | grant |
| Johnson & Johnson Vision Care, Inc. | Johnson & Johnson | local | 2016 | $7,100,000 | | grant |
| The Hertz Corporation | Hertz | state | 2014 | $7,000,000 | | grant |
| Johnson & Johnson Vision Care, Inc. | Johnson & Johnson | local | 2021 | $7,000,000 | | grant |
| ELECTRONIC ARTS - TIBURON | Electronic Arts | state | 2016 | $6,943,336 | | tax credit/rebate |
| Vistakon J&J | | local | 2013 | $6,900,000 | | grant |
| ROA PRODUCTIONS, LLC | | state | 2013 | $6,761,291 | | tax credit/rebate |
| Amazon | Amazon.com | local | 2016 | $6,700,000 | | grant |
| Piper Aircraft, Inc. | | state | 2007 | $6,666,666 | | grant |
| STARZ MIAMI PRODUCTIONS, LLC | | state | 2013 | $6,650,309 | | tax credit/rebate |
| The Boeing Company | Boeing | state | 2011 | $6,640,000 | | grant |
| General Electric | General Electric | local | 2015 | $6,600,000 | | grant |
| Agere Systems | | state | 1999 | $6,500,000 | | grant |
| Silkorsky Aircraft Division | Lockheed Martin | local | 2016 | $6,271,428 | | tax credit/rebate |
| Embraer Aircraft Holding, Inc. | Embraer | state | 2012 | $6,000,000 | | grant |
| ABC Distributing, Inc. | | state | 1998 | $6,000,000 | | tax credit/rebate |
| Embraer Eng.& Tech Center USA, Inc. | Embraer | state | 2013 | $6,000,000 | | grant |
| Citigroup, Inc. | Citigroup | state | 2016 | $6,000,000 | | tax credit/rebate |
| Thales USA, Inc. | Thales | state | 2017 | $6,000,000 | | tax credit/rebate |
| Fidelity National Financial, Inc. & Subsidiaries | Fidelity National Financial | state | 2005 | $5,700,000 | | tax credit/rebate |
| Citigroup, Inc. | Citigroup | state | 2016 | $5,582,400 | | tax credit/rebate |
| Embraer Aircraft Holding, Inc. | Embraer | state | 2008 | $5,500,000 | | grant |
| Telemundo Media LLC | Comcast | state | 2016 | $5,500,000 | | grant |
| WHITNEY BEACH PICTURES, LLC | | state | 2014 | $5,371,889 | | tax credit/rebate |
| Arthrex, Inc. | Arthrex | state | 2017 | $5,300,000 | | tax credit/rebate |
| VT Mobile Aerospace Engineering, Inc. 18-00154 | | State | 2020 | $5,300,000 | | tax credit/rebate |
| Gartner, Inc | Gartner | state | 2018 | $5,280,000 | | tax credit/rebate |
| TVM PRODUCTIONS, INC | | state | 2013 | $5,187,771 | | tax credit/rebate |
| Pope & Land | | local | 2012 | $5,154,000 | | grant |
| POOL MATE PICTURES, LLC | | state | 2015 | $5,014,287 | | tax credit/rebate |
| Chase Bank Card Services | JPMorgan Chase | state | 1997 | $5,000,000 | | tax credit/rebate |
| Pratt & Whitney - Liquid Space Propulsion | RTX Corporation | state | 2000 | $5,000,000 | | tax credit/rebate |
| Fidelity Global Brokerage Group, Inc. | Fidelity Investments | state | 2006 | $5,000,000 | | grant |
| Univision Communications, Inc. | TelevisaUnivision Inc. | state | 2014 | $5,000,000 | | grant |
| VR Laboratories | | local | 2010 | $5,000,000 | | grant |
| Amazon | Amazon.com | local | 2017 | $5,000,000 | | grant |
| Atlantic Sapphire | | local | 2020 | $5,000,000 | | grant |
| The Blackstone Group Inc. | Blackstone | state | 2021 | $5,000,000 | | tax credit/rebate |
| Cunard Line, Ltd. | | state | 1997 | $4,950,000 | | tax credit/rebate |
| Hallmark Partners | | local | 2012 | $4,900,000 | | grant |
| Carrier Corporation | Carrier Global Corporation | state | 2015 | $4,900,000 | | grant |
| Bank of America | Bank of America | state | 2014 | $4,850,000 | | grant |
| Verizon Corporate Resources Group | Verizon Communications | state | 2014 | $4,800,000 | | tax credit/rebate |
| ELECTRONIC ARTS - TIBURON | Electronic Arts | state | 2013 | $4,764,177 | | tax credit/rebate |
| Jabil Circuit, Inc. | Jabil Inc. | state | 2008 | $4,719,000 | | tax credit/rebate |
| Brown & Brown, Inc. | Brown & Brown | state | 2018 | $4,500,000 | | tax credit/rebate |
| SU4, LLC | Lions Gate Entertainment | state | 2014 | $4,496,679 | | tax credit/rebate |
| The Depository Trust & Clearing Corporation | Depository Trust | state | 2004 | $4,400,000 | | grant |
| UPS | United Parcel Service | local | 2016 | $4,300,000 | | grant |
| TVM PRODUCTIONS, INC. | | state | 2014 | $4,260,026 | | tax credit/rebate |
| Palm Coast Data, LLC | New Mountain Capital | state | 2008 | $4,200,000 | | tax credit/rebate |
| Lockheed Martin Corporation 18-01173 | Lockheed Martin | State | 2020 | $4,200,000 | | tax credit/rebate |
| ABR Information Services, Inc. | | state | 1998 | $4,140,000 | | tax credit/rebate |
| TVM PRODUCTIONS, INC. | | state | 2016 | $4,093,902 | | tax credit/rebate |
| Boeing Company | Boeing | state | 1998 | $4,000,000 | | grant |
| Univision Communications, Inc. | TelevisaUnivision Inc. | state | 2012 | $4,000,000 | | grant |
